Albucid compatibility with tetracycline ointment


Symptoms of conjunctivitis

There are such forms of inflammation of the conjunctiva:

  • Bacterial (the disease develops as a result of the penetration of opportunistic and pathogenic bacteria). The discharge of green or yellow mucus is typical. The eyelids swell greatly, vision decreases, and there is pain in the eyes.
  • Allergic (diseases develop as a result of contact of the body with allergens). Allergic conjunctivitis is characterized by severe itching, swelling of the eyelids, and decreased vision.
  • Viral. Redness of the conjunctiva and severe lacrimation are observed. If the appearance of red dots is added to these symptoms, this means that the person has measles. The appearance of bubbles filled with liquid content indicates infection of the body with the herpes virus. With herpes, an increase in body temperature is possible.

All types of conjunctivitis cause a feeling of dryness in the eyes, fear of light, pain and a feeling of sand in the eyes.

Regardless of the etiology of the disease, it occurs in acute or chronic form.

Will oxolinic ointment help against coronavirus: doctors' opinion!

During the period of significant spread of SARS-CoV-2 and the official WHO statement about the absence of medicines to prevent infection, citizens remembered time-tested remedies, including oxolinic ointment. We studied the opinions of doctors whether it will help against coronavirus.

What are anti-coronavirus drugs?

In the absence of effective medicines to prevent coronavirus infection, many people, especially the middle and older generations, use traditional means of preventing infectious diseases.

People who use oxolinic ointment as a means of protecting against coronavirus infection know that it is used to avoid getting infected with the flu, and since the flu is a virus, there is no doubt whether it will help against another viral infection.

People who reject oxolinic ointment as a possible means of prevention cite the following arguments:

It helps against herpes and influenza (supposedly only one type), but is completely useless against a new virus (although studies conducted by the Lvov Research Institute of Epidemiology have shown that the active substance can reduce the incidence of virus infection by almost 45%. With influenza, DAV resistance is maximum, but the 45% result of exposure to the virus is also excellent, especially considering the WHO statement.

No one doubts whether Derinat, an aqueous extract from the milt of sturgeon fish, which has immunomodulator properties, but has not been subjected to systematic scientific research, will help with coronavirus.

But oxolinic ointment as a nasal topical agent is rejected.

Despite the fact that massive research was carried out in the USSR, effective prevention and a milder course of the viral infection were noted.

When answering the question whether oxolinic ointment will help, homegrown experts point to dry mucous membranes, damage to the ciliated epithelium, and even the possibility of contracting coronavirus when applying the product with dirty hands.

However, scientific studies have noted that oxolin has a virucidal effect and prevents the intensive reproduction of the virus in living cells.

Herpes viruses, molluscum contagiosum, influenza, adenoviruses, and wart viruses are sensitive to its action. Is this ointment against coronavirus as useless as can be concluded from the opinions of such authors, or is there still some point in its use?

It's worth thinking about the facts

In 1999, scientific studies were published in the Chemical-Pharmaceutical Journal that proved the undeniable activity of oxolin as a prophylactic agent.

Some new publications question whether oxolin will help against SARS-CoV-2 on the grounds that no research was carried out in the USSR on the active compound's abilities against coronaviruses, despite the fact that they were known already in 1965.

It does not hurt such specialists to remember that:

“The state paid for research on pressing practical problems, such as influenza. And the isolated virus with corona was then included in a whole bouquet of pathogens with a relatively harmless diagnosis of ARVI. If it were an urgent problem, oxolin would, without a doubt, be tested in relation to the coronavirus.

Oxolinic ointment at a concentration of 3% has neither irritating nor toxic effects. About 30% of the applied product is absorbed on the mucous membrane.

Those who use it during seasonal epidemics rinse their nose with saline solution before applying the product and after returning from the street.

There is no evidence of drying out of the mucous membrane during a short trip outside, and the saline solution perfectly cleanses it of impurities.

If a person is convinced that he is using an effective prophylactic drug, the placebo effect also works. Psychological attitude is important during epidemics, when the risk of infection is also due to a depressive state.”

There is no point in rejecting proven drugs with proven antiviral effects on the basis that they were developed in Soviet times. Otherwise, you will have to give up activated carbon, allohol, and other time-tested remedies and drugs.

Let's summarize.

Oxolinic ointment is a well-known remedy with a virucidal effect.

When applied for a short time, it has neither irritating nor toxic effects.

It has been proven to resist the virus in 45% of cases.

It does not dry out the mucous membrane if you rinse your nose with saline solution upon returning from the street.

It's quite inexpensive.

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Source: https://zen.yandex.ru/media/tutkleva/pomojet-li-oksolinovaia-maz-ot-koronavirusa-mnenie-vrachei—5e8ee7c3239c344cd9ec2148

The effectiveness of ointment treatment

The effectiveness of therapy depends on how correctly the drug is selected. The patient must constantly comply with the dosage of the drug and its regimen.

These drugs themselves are potent. However, they are often used in combination with other remedies (if the disease is advanced). At the initial stage of development of the pathology, it can be eliminated in a few days. In the later stages of pathology development, the effectiveness of therapeutic measures decreases: drops must be taken together with other medications.

Antiviral agents Zhytomyr Pharm.f-ka LLC DKP Oxolinic ointment – ​​review

Oxolinic ointment is familiar to everyone. About 25 years ago, this drug was almost a panacea, when there was nothing on the shelves of pharmacies except analgin and citramon and they were treated with ant herbs. They prayed for her and pinned their hopes on her.

I still remember Soviet times and remember how, before going to kindergarten/school, my mother smeared some white ointment on my nose. At that time, I still did not understand the importance of this ritual, and I continued to regularly pick up an infection somewhere. Even as a child, I realized that Oxolinic ointment is a drug that works selectively, and not for all segments of the population

Nevertheless, although I consider Oksolinka a rather controversial drug, it is still always in the medicine cabinet.

Now the topic of cold medications is very relevant, so I hasten to share my opinion about Okoslin ointment and its effect. Does it help during flu epidemics?

Oxolinic ointment

  • Place of purchase: pharmacy
  • Cost: about 11 UAH
  • Volume: 10 grams
  • Manufacturer: “DKP Pharmaceutical Factory”, Zhitomir, Ukraine

Oxolinic ointment is credited with such miraculous properties, having learned about which, I was a little shocked, given the fact that the effectiveness of this drug has not yet been proven (for a second, Oksolinka was discovered back in the 70s).

Here you can treat the runny nose, viral eye diseases, lichen, molluscum contagiosum, and much more, wherever human imagination can stretch.

I was sinful, I used Oxolinic ointment for its intended purpose - for the prevention of influenza and ARVI, for other purposes there was no need for now, but even if it was necessary, I would give preference to other drugs with proven effectiveness.

Oxolinic ointment / Efficiency

Some sources recommend using Oxolinka for a runny nose. Yes, there is a grain of truth in this, because most often a runny nose is caused by a virus, and the active ingredient in Oxolinic ointment blocks the proliferation of a viral infection.

The same applies to a viral eye infection - viral conjunctivitis, although for this purpose I prefer the Okoferon drop. After all, the ointment is distributed worse over the mucous membrane, collects in lumps, is absorbed slowly, and therefore the effect will not come as quickly (compared to drops).

Oxolinic ointment for runny nose and eye inflammation

Oxolinic ointment can be used even for diseases such as human papillomavirus infection and dental diseases of the oral cavity.

Papillomas on the mucous membrane and on the skin (they especially “love” the neck area), warts - all these “troubles” are caused by the human papillomavirus. By the way, 70% of all humanity are carriers of this virus. In this case, Oxolinic ointment can hypothetically help. But as for stomatitis, which is most often caused by bacteria and fungus, this is a very controversial issue.

These two diseases are well known to me, but at one time I cured the first with a solution of celandine (burned out the papillomas), and the second with the help of Metrogyl-Dent. Give preference to them rather than to a drug whose effectiveness has not been proven.

Oxolinic ointment for warts and papillomas and for stomatitis

I also found information that Oxolinic ointment can cure herpes zoster and molluscum contagiosum. As for the second, I don’t presume to say, but having worked in a pharmacy for several years, I know for sure that the drug of choice No. 1 for herpes zoster is Acyclovir ointment. Either our doctors don’t trust Oksolinka, or they themselves are not aware that such a treatment regimen exists.

Oxolinic ointment for herpes zoster and molluscum contagiosum

Let's move closer to the characteristics of the drug .

The packaging of the ointment is simple: a cardboard box in which an aluminum tube is placed. The opening of the tube was initially protected; to open it, you need to pierce the protective membrane with the back of the cap.

The ointment is very oily, has a transparent white color and a fairly neutral odor. The ointment does not spread very easily over the skin and mucous membranes; when applied to the nasal mucosa, it takes a very long time to be absorbed, but I see this as its advantages, because the mucous membrane does not dry out even in the cold (but it is very visible on the hairs inside the nose - the other side of the coin).

Indications

As I mentioned above, Oxolinic ointment has plenty of indications, which is amazing in our time for a drug that has not been tested at all and has never been proven to be effective. This is probably why this drug is not so popular among doctors - they practically do not prescribe it (with the exception of children, pediatricians love it).

Oxolinic ointment / Indications

Detailed instructions for the drug:

Regarding the discovery of Oxolinic ointment: the active ingredient of this drug was registered more than 45 years ago. And for me it is very strange that no one has undertaken to prove its effectiveness.

Discovery of Oxolinic ointment

Contraindications:

  • tendency to an allergic reaction to Oxolin or Vaseline
  • periods of pregnancy and breastfeeding;
  • children's age (there is not enough information on the use of the drug in pediatrics).

All manufacturers of Oxolinic ointment decided to protect themselves and add pregnancy, lactation and childhood to contraindications. But statistics show that Oksolinka is the favorite drug of this category of citizens.

All drugs are generally contraindicated for pregnant women; even homeopathy is prescribed to them with caution, let alone synthetic drugs.

But the fact remains that Oxolinic ointment is a harmless drug for the prevention of ARVI in pregnant women, because it is an external agent, which means it does not have a systemic and does not have a cumulative effect.

Oxolinic ointment is also allowed for children in the first year of life, but you should take into account the fact that the dosage of this ointment varies and you need to buy the weakest (0.25%).

If you consider even this concentration to be high, then you can first mix this ointment with some kind of fatty base (the same Vaseline or baby cream).

You just need to mix it immediately before use, but do not prepare this mixture for future use.

Oxolinic ointment during pregnancy

Side effects:

burning sensation, superficial dermatitis, thin, watery nasal discharge

I have never noticed any side effects.

Application and dosage:

Oxolinic ointment is used only externally (skin + mucous membranes). Apart from the prevention of ARVI, I don’t use it anywhere else. I apply it to the nasal mucosa with a cotton swab and distribute it as carefully as possible so that there are no white lumps of ointment left on the hairs. To make sure that the ointment is absorbed, I massage the wings of my nose.

Oxolinic ointment / Application and dosage

My observations and results

For several years now (if not a decade), Oksolinka has been a permanent resident of my medicine cabinet. According to tradition, starting from the autumn-snotty period, ending with April-May, we together and persistently smear our noses with this miracle ointment)) Either out of habit, or hoping for a miracle...

I wouldn’t say that the effect from her is terrible, but nevertheless, it’s somehow calmer with her. And in order to enhance the preventive effect, I use several more drugs in abundance.

At the moment, my family is being prevented as follows:

  • Laferobion (at a dosage of 100 thousand, drop into the nose)
  • Marimer spray (sea water, rinse the nose twice a day)
  • Rimantadine (antiviral drug, 1 tablet per day)
  • vitamin C (at a dosage of 500 mg, 1 tablet daily)
  • Oxolinic ointment before going outside

Prevention of influenza and ARVI

I cannot call Oxolinic ointment an effective drug that alone will protect you and your family from colds during a raging epidemic. But! If you come into contact with a person who has a cold, and start using this drug in advance, then rest assured that you either will not get sick, or the course of your illness will be quick and mild. You'll get away with a slight fright, as they say.

But as for those moments when you already feel that you are sick, I hasten to disappoint you - Oxolinic ointment cannot cope alone; you need reinforcement in the form of interferon inducers (Amiksin, Lavomax, Cycloferon, etc.).

As for my experience, Oxolinic ointment did not help me as often as I would like. In 2020, I caught a cold four times, two of which had complications in the form of otitis media and conjunctivitis, and two times ended with bronchitis and chronic tonsillitis.

But it helps my husband; this year he only got sick twice and each time the course of his illness was limited to three days (he sniffled a little and was healthy, as cheerful as a cucumber).

conclusions

Summarizing the above, I can safely call Oxolinic ointment a controversial drug. not even because its effectiveness has not been proven, but from my personal experience I was convinced that the drug does not always help and not everyone. It’s like homeopathy, if you believe it will help, if not, then hurt yourself))

Personally, I can recommend that since you are being prevented with Oxolinic ointment, do not neglect other drugs - it’s more reliable.

Even in our very “expensive” times, you can find budget medications. For prevention, echinacea tincture, interferon for instillation into the nose, saline solutions, the same Remantadine and loading doses of vitamin C are good.

Do not be ill!

Reviews on anti-cold topics:

Source: https://irecommend.ru/content/vse-o-samom-spornom-preparate-oksolinovoi-mazi-dokazana-li-ee-effektivnost-pomogaet-li-vo-vr?expand-all-comments

The choice of ointment depending on the form of conjunctivitis

There are ointments:

  • antimicrobial;
  • antiviral;
  • hormonal;
  • antihistamines.

Ointments for bacterial conjunctivitis

When treating conjunctivitis of microbial origin and to eliminate fungi, it is advisable to take antibacterial medications. The most effective of them are:

Tetracycline ointment

It contains the active substance tetracycline. It disrupts the processes of DNA formation in bacterial cells. Because of this, protein synthesis is inhibited and the bacterium dies. Tetracycline is active against many gram-positive and gram-negative organisms.

The peculiarity of the ointment is its low absorption, i.e. the active component does not penetrate into the blood. Tetracycline is allowed to be taken by pregnant women.

Tobrex

This is an ointment for urgent relief of symptoms of conjunctivitis. The active substance is tobracymine. Suitable for treating children. Tobrex is a broad-spectrum drug.

Erythromycin

This is a widely used ointment for the treatment of bacterial conjunctivitis. The active substance is destructive to most bacteria. Used for the treatment of barley, inflammatory diseases of the mucous membrane.

Before starting use, you need to determine the sensitivity of the microflora that caused the disease. When using the ointment, a slight local irritant effect is possible.

Phloxal

This is a new generation antibacterial drug. The active substance is ofloxacin. It is characterized by a fairly wide range of effects. Floxal fights infectious agents against which penicillin and cephalosporin drugs are inactive.

The product is used to prevent infections after eye surgery.

Levomycetin

This ointment is used for conjunctivitis, as well as for the purpose of prevention under conditions of an unfavorable epidemic threshold. Levomycetin destroys bacteria sensitive to methyluracil and chloramphenicol. It can also be used to treat childhood conjunctivitis.

Sintomycin

The ointment is used for the treatment of inflammatory pathologies of the mucous membrane of the eyes. Contains chloramphenicol. Relieves eye redness, swelling and itching. An analogue of the drug is Levomekol.

Antiviral drugs

They are used to treat viral conjunctivitis. As auxiliary components they contain moisturizing substances that quickly relieve the main symptoms of diseases.

Oxolinic ointment

It is the best remedy for the treatment of viral eye pathologies. The peculiarity of the drug is the absence of side effects. Gives high results in the treatment of viral conjunctivitis and can be used in childhood.

When used correctly, it has virtually no side effects.

Acyclovir

This is an antiviral agent that is often used in ophthalmic practice to treat viral eye diseases. Indicated for herpetic keratitis caused by the activity of the herpes simplex virus. Not for use during pregnancy and breastfeeding.

Hydrocortisone ointment

This drug belongs to glucocorticosteroids. The active ingredient is hydrocortisone acetate. It is actively used to treat viral conjunctivitis, eyelid diseases and reduce allergies.

Solcoseryl

Used to speed up recovery processes and eliminate the consequences of viral conjunctivitis. The active substance is extracted from cattle blood dialysate.

Bonafton

This is a common antiviral drug. The active substance is bromonaphthoquinone. The drug is used to treat herpes and viral keratitis.

Dexa-gentamicin

This is a combination remedy that includes an antiviral substance and corticosteroids. Includes gentamicin and dexamethasone. It has an antiviral and antihistamine effect. Dex-gentamicin is used to treat advanced viral conjunctivitis.

Fenistil Pencivir

This is an ointment for the treatment of herpetic conjunctivitis. It is prescribed for 4 days, and the frequency of administration can be up to 8. The drug is contraindicated during pregnancy.

Antiallergic drugs

To treat allergic conjunctivitis, any contact with the allergen should be avoided. To relieve symptoms, ointments containing hormonally active components are used. The drugs in this group have a pronounced anti-allergic and anti-inflammatory effect.

Any glucocorticosteroid drugs should not be taken by children, pregnant or lactating women. And their use is permissible only as prescribed by a doctor. These medications are not used for fungal and bacterial infections of the conjunctiva.

Maxidex

The active substance of this drug is dexamethasone. Maxidex is used regardless of the severity of the conjunctival disease. Apply to the lower eyelid up to 8 times a day.

Tobradex

Refers to combination drugs containing dexamethasone and tobramycin (an antibiotic with a broad spectrum of action). Tobradex must be placed behind the lower eyelid up to 8 times a day.

Eubetal

The combination drug consists of betamethasone, tetracycline, chloramphenicol, sodium colistimethate. It has a complex antibacterial, anti-inflammatory, anti-allergic effect. Eubetal is placed behind the lower eyelid 3 to 4 times a day. Do not take if you have glaucoma or damage to the cornea.

Cortineff

Glucocorticosteroid ointment with the active ingredient fludrocortisone. A small amount of the drug is placed behind the lower eyelid up to 3 times a day. The duration of therapy can be up to 2 weeks (in especially severe cases, more).

Sometimes side effects occur - increased pressure inside the eye, disruption of the integrity of the cornea.

Garazon

Glucocorticosteroid ointment, which contains an added antibiotic. Has a pronounced antiallergic effect. Garazon is contraindicated in case of hypersensitivity of the body to betamethasone or gentamicin, fungal diseases and tuberculosis.

The best ointments for bacterial conjunctivitis

There are many antibacterial ointments that can help with such ailments as conjunctivitis.

The following received the best reviews:

  1. Erythromycin. A popular topical antibacterial agent that contains an antibiotic from the macrolide group.
  2. Levomekol. The drug contains chloramphenicol, an antibiotic, the active substance dioxomethyltetrahydropyrimidine, methyluracil and additional components (polyethylene oxides). Chloramphenicol destroys most bacteria (rickettsia, spirochetes, chlamydia), inhibiting the protein in the cells of microorganisms. Levomekol works very well for purulent conjunctivitis, quickly eliminating foci of inflammation.
  3. Tetracycline ointment. The most common drug for killing various types of bacteria, which has earned positive reviews. The composition contains tetracycline, an antibiotic that is practically not absorbed into tissues and blood, which significantly reduces the number of side effects.
  4. Phloxal. The product contains Ofloxacin, which has a detrimental effect on many microbes.
  5. Colbiocin. A combined product containing tetracycline, sodium colistimethate, and chloramphenicol, which are effective against a large number of bacteria.
  6. Korneregel. Suitable for the treatment of any type of conjunctivitis, including bacterial. Should only be used in combination with other drugs. Prohibited for pregnant women.

Rules for applying ointment

The ointment should be applied to the eyes carefully and in strict order:

  1. Before applying the ointment and before squeezing it onto your finger, you need to wash your hands thoroughly. If a medical stick is used to apply the ointment, it must be sterilized with an antiseptic drug.
  2. You need to put the medicine in those moments when your eyesight has not been strained for the last hour. It should be borne in mind that masks may temporarily reduce visual acuity.
  3. You should sit down and tilt your head back.
  4. The eyelid is pulled back using two fingers. The ointment is applied with your finger to the tip of the eyelid.
  5. Then you need to sit for 1-2 minutes with your eyes closed.
  6. Excess ointment is removed with a clean napkin.

Instructions for use

Note! Adults and children are prescribed ointment in different dosages, and the duration of therapy also differs.

Children require a more gentle treatment regimen.

For adults

The ointment is carefully placed in a thin layer into the conjunctival sac , pulling the lower eyelid of the inflamed eye with the index finger of the other hand.

A cotton swab is often used to apply the ointment .

In this case, it is recommended to remove the lenses in advance and you can put them on no earlier than 30-40 minutes after using the product.

The procedure should be performed 2-3 times a day (until signs of conjunctivitis disappear).

For children

Stay up to date! Levomekol is indicated for children over 3 years of age, but in extreme cases (under medical supervision), the ointment is prescribed to children under the age of one year.

However, the dosage should be minimal and the drug can be used for no more than 3-4 days .

Otherwise, side effects are possible in the form of an allergic rash, itching and irritation of the skin around the eyes and more.

The application method is as follows:

  1. The inflamed eye is washed with either chamomile infusion (1 tablespoon of dry herb per glass of boiling water, cool and strain), or Furacilin solution (1 tablet crushed and dissolved in a glass of boiled water at room temperature). This procedure is especially relevant for children with purulent conjunctivitis.
  2. 10-15 minutes after washing the eye, you can start applying the ointment. To do this, a small amount of the product (the size of a small pea) is carefully placed in the conjunctival sac.

You should know! The procedure should be performed no more than 2 times a day.

In case of allergic reactions and deterioration of the baby's condition, treatment should be stopped and consult a pediatric ophthalmologist.

The drug is recommended to be used with caution in children with weakened immune systems who are prone to allergic reactions to chemicals and medications.

To make sure there is no allergy, Levomekol must first be applied to the child’s dry skin (for example, in the wrist or elbow area) and observed for an hour to observe the body’s reaction.

Consumer Reviews

Irina: For bacterial conjunctivitis I used Tetracycline ointment. She coped with the manifestations of bacterial infection of the conjunctiva. I applied the ointment 4 times a day for 5 days. During this time, the manifestations of the disease passed, and vision was not affected.

Olga: Acyclovir ointment saved me from viral conjunctivitis. I used it 4 times a day. On the third day, the manifestations of the disease became less pronounced. I was treated with this ointment for 5 days. There were no relapses of the disease.

Drug interactions

The effect of the antibiotic in the composition is inhibited by the use of medications such as:

  • cytostatics;
  • sulfonamides;
  • pyrazolone derivatives.

Levomekol tablets do not exist, since chloramphenicol is not taken orally due to strong side effects. Methyluracil tablets are indicated in the complex treatment of gastric and duodenal ulcers, the effects of chemotherapy, radiation exposure, and to improve the healing of fractures.

Adults are given a whole tablet of 0.5 g, children - half (0.25 g) after meals 3 times a day. The duration of the course is determined by the disease and ranges from 10 days to one and a half months.

Levomecol should not be used simultaneously with other ointments of similar action: in this case, the effectiveness of both drugs will be reduced. Does not interact with oral medications, as it bypasses the circulatory system.

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