Use of the drug Furadonin during pregnancy and lactation against urological diseases

Description of the drug Furagin

Furaginavexima is a drug whose main component is furazidin. This is an antimicrobial substance whose spectrum extends to gram-positive cocci. Enterococci and proteus bacteria are resistant to it. The pharmacological action is associated with the suppression of nucleic acid production. Biochemical processes in the cell are inhibited, so they stop reproducing.

If the drug is used in small concentrations, a bacteriostatic effect is formed, and at high doses it is bactericidal.

Absorption of the active substance occurs in the intestines. The maximum concentration in the blood is observed after 3-7 hours. It is at this moment that the therapeutic effect is formed. The drug is indicated for use in infectious and inflammatory diseases of the following parts of the body:

• excretory system;
• genitals;

• treatment and prevention of bacterial infection of the skin and soft tissues, for example, with burns;
• oral cavity, pharynx.

There are few side effects. Dyspeptic disorders, polyneuritis, dizziness, and rash are distinguished. The drug is contraindicated during pregnancy and lactation, children under 4 years of age. It is important to determine whether the patient has individual intolerance before prescribing. To prevent negative effects, first learn how to take Furagin for cystitis or other pathologies in women and other patients.

Features of Furadonin

Furadonin is an antimicrobial agent based on nitrofurantoin. When patients ask whether Furadonin is an antibiotic or not, the specialist will answer that it is more of an antiseptic. Its activity occurs against Klebsiella, Enterobacteriaceae, and Proteos. The effect on pathogenic microorganisms is limited. The drug in low concentrations inhibits the proliferation of bacteria, in high concentrations it destroys them.

Absorption occurs in the digestive tract. Bioavailability is average. Communication with blood proteins is above 60%. A special feature of the product is its penetration through the blood-brain and placental barrier. Excretion is carried out through the kidneys. The following indications for use are distinguished:

• pyelonephritis;
• cystitis;

• urethritis.

From the indications it is clear that the drug affects only the urinary system and is not used for genital infections. The product has many side effects. They are formed from the respiratory, digestive, nervous systems, hematopoiesis, and immunity. Drug fever, inflammation of muscles and joints, and flu-like symptoms may occur.

In patients who exceed the course of use or dosage, superinfection often occurs.

The drug is contraindicated in severe liver or kidney diseases. It should not be taken during pregnancy, lactation, or for children under 1 month. It is prohibited to use the product for heart failure or porphyria.

Furadonin: description of the medication, features of use for hepatitis B

Lactation is a crucial period, which is overshadowed by infectious diseases such as cystitis.

The disease occurs due to injury to the bladder, non-compliance with sanitary rules by the nursing mother, hypothermia with a cold compress after childbirth, etc.

Unpleasant symptoms disrupt the usual way of life and spoil the mood, which the baby invariably feels; he becomes capricious and cries. Therefore, it is necessary to find a safe and effective drug as soon as possible.

Furadonin is an antimicrobial drug from the nitrofuran group, which is used to treat infectious and inflammatory diseases of the genitourinary tract. Information about the drug, the possibility of its use during lactation - more on this below.

Description of the drug

Furadonin is a synthetic antimicrobial drug that stops the proliferation of bacteria and destroys them.

The main active ingredient of the drug is nitrofurantoin. Additional components: pyrogenic silicon dioxide, starch, calcium salt of stearic acid.

Dosage forms: tablets, dry mixture for oral administration. The tablets are coated, which dissolves when it enters the digestive tract.

Furadonin has a pronounced bactericidal effect; it disrupts protein production in bacteria and the permeability of the cell membrane. The components of the drug are effective against Shigella, streptococci, staphylococci, Escherichia coli and other gram-positive and gram-negative microorganisms. They stop the development of bacteria and destroy them.

Bacteria become accustomed to the active substances in rare cases, but with prolonged use it is possible.

Indications

Furadonin is indicated for bacterial infections of the genitourinary tract:

• Inflammation of the renal pelvis;
• Kidney inflammation;
• Cystitis;
• Inflammation of the urethra (urethra).

Read more about inflammation of the urinary tract (cystitis) here.

The drug is used to prevent infectious diseases during cystourethroscopy, urological procedures, and catheterization.

Method of application and dosage

To prevent digestive disorders, take Furadonin after meals or take the tablet with a large volume of liquid (still water, milk). The tablets have a bitter taste and are therefore not recommended to be chewed. The maximum daily dose for an adult patient is 600 mg, a single dose is 300 mg.

Difference between Furagin and Furadonin

When prescribing treatment, the doctor must explain to the patient what the difference is between Furagin and Furadonin. This is important when selecting therapy for patients who have chronic diseases of various organs or intolerance to certain substances. Distinctive properties are presented in the table.

From the distinctive features it is clear that Furagin is a more gentle remedy, as it has fewer side effects. It destroys significantly more pathogenic microorganisms than Furadonin. But if we are talking about young children, it is better to use Furadonin. It is approved even for infants from 1 month, as it does not affect the growth and development of internal organs, the function of the central and peripheral nervous system.

Furadonin price, where to buy

The price of Furadonin 50 mg tablets is on average 55 rubles. per pack 10 pcs. The average price of Furadonin 100 mg is 100 rubles. per pack 20 pcs.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Furadonin Avexima tablets 50 mg 20 pcs. JSC Irbitsky HFZ
  114 rub. order
• Furadonin tablets 100 mg 20 pcs. Olainfarm JSC

  170 rub. order

• Furadonin Avexima tablets 50 mg 10 pcs. JSC Irbitsky Chemical Plant

  73 rub. order

• Furadonin tab. 50 mg 20 pcs. YuzhPharm LLC

  73 rub. order

• Furadonina tab. 50 mg No. 10 YuzhPharm LLC RU

  48 RUR order

Pharmacy Dialogue

• Furadonin tablets 100 mg No. 20Olainfarm OA

  160 rub. order

• Furadonin Avexima tablets 50 mg No. 20 Irbitsky HFZ

  106 rub. order

  Read also:  Use of erva woolly for urolithiasis
• Furadonin Avexima tablets 50 mg No. 10 Irbitsky HFZ

  67 RUR order

• Furadonin Avexima (tab. 100 mg No. 20) Irbitsky Chemical Plant

  RUB 179 order

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Pharmacy24

• Furadonin 0.1g No. 20 tablets AT "Olainfarm", Latvia
  49 UAH. order

PaniPharmacy

• Furadonin tablets Furadonin tablets 0.1g No. 20 Latvia, Olainfarm JSC

  51 UAH order

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Furagin, Furadonin or analogues

When using antimicrobial agents, you should carefully read the instructions for use. It indicates for which organs and systems the drug can be used. For example, the medicine Furasol is used only locally, externally. Analogues such as Furagin, Furadonin, Nolitsin, Nitroxoline are used orally. Therefore, they destroy the infection located in the internal organs. Most of them affect the urinary and reproductive systems.

While using the chosen product, it is recommended to conduct a general blood and urine test. The data shows how much the medicine affects the body. If the patient’s blood cell ratio changes dramatically or urine analysis worsens, the drug is discontinued. They are looking for an analogue that will not have similar side effects.

Before prescribing a medication and or choosing a substitute, a medical history is taken. It is important to identify which substances the patient has individual intolerance and allergic reactions to. Possible cross-reaction with the prescribed drug. Therefore, for allergy sufferers, medication selection is made with caution. Most of the drugs presented penetrate only the urinary and reproductive systems, without affecting other internal organs. Therefore, the main indication for use is infection of these parts of the body.

FURADONIN

Side effects

Classification of adverse reactions by frequency of development: very often (≥ 1/10);
often (≥1/100 to <1/10); uncommon (≥ 1/1000 to < 1/100); rare (≥ 1/10,000 to < 1/1000); very rare (< 1/10000); * - not known (cannot be determined from the available data). Gastrointestinal disorders:

often - nausea, vomiting, lack of appetite, the frequency and severity of which depends on the dose. Rarely - diarrhea, pancreatitis; abdominal pain*. The frequency of side effects decreases when taking the drug with food and plenty of liquid.

Infectious and parasitic diseases:

pseudomembranous colitis

Nervous system disorders:

often - headache. Dizziness*, asthenia*, nystagmus*, drowsiness*. Rarely - increased intracranial pressure. In some cases: in patients with liver failure, anemia, diabetes mellitus, electrolyte imbalance, deficiency of B vitamins, serious peripheral polyneuropathy is possible, the first symptoms of which are a feeling of numbness and burning in the legs, muscle weakness. If the symptoms mentioned above occur, the drug should be discontinued.

Disorders of the respiratory system, chest and mediastinal organs:

acute and chronic reactions of pulmonary hypersensitivity, characterized by fever, eosinophilia, cough, chest pain, shortness of breath. Interstitial changes in the lungs and broncho-obstructive syndrome are possible. Pulmonary infiltrate or consolidation and pleural effusion may appear within hours or days of initiation of therapy; they usually resolve after stopping the drug. Subacute or acute pulmonary symptoms, including pulmonary fibrosis, may develop insidiously in patients with prolonged therapy; fibrosis may be irreversible, especially if therapy is continued after the onset of symptoms. When the first reactions of hypersensitivity of the lungs appear, the drug should be discontinued.

Disorders of the liver and/or biliary tract:

rarely hepatitis, cholestatic jaundice (dose-independent and disappear after discontinuation of the drug).

Disorders of the track and subcutaneous tissues: often allergic reactions - skin rashes, urticaria, itching; in some cases - inflammation of the salivary glands, exfoliative dermatitis, polymorphic erythema.

Blood and lymphatic system disorders

: rarely - megaloblastic anemia, leukopenia, granulocytopenia or agranulocytosis, thrombocytopenia, hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency.

Immune system disorders:

in some cases - angioedema, anaphylaxis. In some cases, autoimmune reactions, mainly associated with chronic changes in the lungs or liver. Symptoms of this lupus-like syndrome are rash, eosinophilia, fever, arthralgia, short-term eosinophilia, and an increase in at least two parameters is observed in the blood serum - antinuclear antibodies, antibodies to smooth muscle or to the glomerular basement membrane, and Coombs' reaction.

Disorders of the genital organs and breast:

in very rare cases - a passing disorder of spermatogenesis.

Other:

rarely - joint pain, reversible hair loss.

If any side effects occur that are not listed in these instructions, or if any of the side effects mentioned are particularly severe, you should consult your doctor about the advisability of further use of the drug.