Furagin or Furadonin. What is best for the treatment of cystitis

Which is better for cystitis - Furagin or Furadonin - depends on the characteristics of the course of the disease. The problem is that only doctors take them into account when prescribing medicine. Patients themselves try to choose a cheaper remedy, even if in their situation it shows less effectiveness and leads to side effects. Furagin is similar in name and active ingredients to Furadonin, but you cannot replace one medicine with another without a doctor’s recommendation.

Comparison of the effectiveness of Furagin and Furadonin

The effectiveness of Furagin is quite similar to Furadonin - this means that the ability of the medicinal substance to provide the maximum possible effect is similar.
For example, if the therapeutic effect of Furagin is more pronounced, then using Furadonin even in large doses will not achieve this effect.

Also, the speed of therapy - an indicator of the speed of therapeutic action - is approximately the same for Furagin and Furadonin. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.

Characteristics of Furagin

Pathogens do not develop sensitivity to the active substance Furagin furazidine for a long time. Including gram-negative and gram-positive bacteria that can provoke the development of cystitis.

Furagin has shown numerous therapeutic effects:

• relief of acute and chronic inflammatory processes;
• normalization of urination;
• stimulation of edema resorption;
• reduction in the severity of pain.

Its antimicrobial effect is based on the binding of bioactive substances in bacterial cells responsible for the transfer of hydrogen molecules. Microbes lose the ability to build membranes, so their reproduction slows down and then stops altogether.

Comparison of safety of Furagin and Furadonin

The safety of a drug includes many factors.

At the same time, in Furagin it is quite similar to Furadonin. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing metabolism in Furagin, as well as in Furadonin, we look at which organ is the metabolizing organ and how critical the effect on it is.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Furagin does not have any risks when used, just like Furadonin.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of the use of Furagin and Furadonin.

Which drug is better

Furagin or Furadonin is selected and prescribed by the doctor based on the clinical picture. The first medicine will be prescribed:

• people with diseases of other organs to reduce the risk of complications;
• children due to the simple calculation of dosage and the small number of contraindications.

Preference will be given to Furadonin:

• in advanced cases and in severe cases of the disease;
• for the treatment of chronic processes;
• when cystitis is complicated by prostatitis.

The drugs are similar in their mechanism of action, but due to different active ingredients they provoke different side effects. You cannot replace one drug with another on your own.

Comparison of addiction in Furagin and Furadonin

Like safety, addiction also involves many factors that must be considered when evaluating a drug.

So, the totality of the values ​​of such parameters as “o syndrome” in Furagin is quite similar to the similar values ​​in Furadonin. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, in Furagin the meaning of the “syndrome” is quite small, however, the same as in Furadonin.

Characteristics of Furadonin

A comparison of the mechanisms of action of Furagin and Furadonin helps the doctor understand what is best to prescribe. They are similar, but there are also significant differences.

The active substance Furadonin nitrofurantoin, upon contact with bacterial cells, inhibits the production of ergosterols. And without these proteins, their reproduction is impossible. Cells become easily permeable to intercellular fluid with microelements dissolved in it, which causes their destruction.

Furadonin is in demand in the treatment of cystitis caused by the following pathogens:

• shigella;
• streptococci;
• Klebsiella;
• Proteus;
• staphylococci;
• coli.

The doctor’s decision about what is better to prescribe for the treatment of cystitis - Furagin or Furadonin - depends on the severity of the infection. With an acute disease, there is no time to wait for the tablets to dissolve. Therefore, preference is given to Furadonin. Unlike Furagin, the drug is produced not only in the form of tablets, but also in the form of a powder for preparing a suspension.

Comparison of side effects of Furagin and Furadonin

Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.

Furagin's level of adverse events is almost the same as Furadonin's. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Furagin are similar to Furadonin: how quickly the body recovers after taking it and whether it recovers at all.

Similarities and differences between furagin and furadonin

The active ingredients of both drugs, nitrofuran derivatives, have a negative effect on gram-positive and gram-negative bacteria in the genital tract. At the same time, the active substance of Furadonin - nitrofurantoin - acts more aggressively.

Furagin has a mild effect, but its effectiveness is lower. Doctors know about this, so Furagin is prescribed in combination with antibiotics. When taking Furadonin, antibiotic therapy is not necessary, but this drug does not completely replace them. If you use it without antibiotics, the treatment will last longer.

The drugs differ in dosage form. Furadonin is supplied only in the form of capsules and tablets. Furagin can be found in powder form.

When is it prescribed?

Furadonin is prescribed for various infections of the genitourinary system in men and women. The medicine is effective for cystitis complicated by prostatitis, as well as inflammatory processes in the kidneys and urinary tract. Taking these cystitis tablets treats chronic bacterial urinary tract infections.

Furagin is also prescribed for infectious diseases of the urinary and genital tract, but the range of use of this drug is wider. It is also used to disinfect wounds and treat ulcers. The components of the drug stop bleeding and prevent infection. For this reason, it is used for cystitis complicated by wound formation in the urinary tract. The drug is ineffective for the treatment of chronic forms of diseases.

Furagin and Furadonin are also used as infection prevention before surgical interventions and endoscopic examinations.

How to use

When learning what the difference is between Furagin and Furadonin, you should first of all pay attention to the dosage. Since the second drug has a stronger active ingredient, its dose is on average lower than that of Furagin, and the treatment period is shorter. The differences are clearly visible in the table.

The table shows the dosage for adults. Children over 12 years of age are prescribed the medicine in the same proportions. For children under 12 years of age, the dosage of Furadonin is calculated individually by the doctor; use is permitted after reaching 1 month. The second drug can be used in children from 1 week old; the dosage is calculated depending on the child’s weight and is 5-7 mg per 1 kilogram.

Most urologists often prescribe Furagin for children. This decision is due to the fewer side effects of the drug, as well as its availability in powder form. It is easier for parents to measure its dosage than to cut a Furadonin tablet into several parts.

Contraindications

Some of the contraindications for both drugs are the same:

• individual intolerance to nitrofurans;
• period of pregnancy and breastfeeding;
• renal failure;
• impaired synthesis of the enzyme glucose-6-phosphate dehydrogenase.

This concludes the list of contraindications for Furagin. Furadonin has additional prohibitions on use. These include:

• Liver diseases, risk of liver failure.
• Pathologies of the cardiovascular system leading to cardiac dysfunction.
• Systemic diseases such as anemia, diabetes mellitus, electrolyte imbalance, excess B vitamins. In patients with such diagnoses, Furadonin causes damage to peripheral nerves.

In terms of the number of contraindications, Furagin differs from Furadonin for the better. Therefore, people who often experience adverse drug reactions are most often prescribed the first drug. The dosage of the medicine may be reduced.

Side effects

Due to the similar active ingredients, the side effects from taking the drugs differ little. Both medications sometimes cause:

• Increased body temperature, muscle pain, weakness. These symptoms disappear after stopping the drug.
• Relapse of dermatitis, allergic rash, blisters on mucous membranes.
• Gastrointestinal tract dysfunction: loss of appetite, vomiting, diarrhea.

Furadonin can cause side effects that do not appear during Furagin therapy. These include:

• disorders of nervous activity: irritability, fatigue, uncontrolled movements of the eyeballs, tremors in the limbs.
• pathologies in the respiratory system: chest pain, difficulty breathing.

The list of side effects, as well as contraindications, for this medicine is higher. Therefore, it is rarely prescribed to people who are at risk, that is, have a history of pathologies of the respiratory, nervous, cardiovascular and digestive systems.

Comparison of ease of use of Furagin and Furadonin

This includes dose selection taking into account various conditions and frequency of doses. At the same time, it is important not to forget about the release form of the drug; it is also important to take it into account when making an assessment.

The ease of use of Furagin is approximately the same as Furadonin. However, they are not convenient enough to use.

The drug ratings were compiled by experienced pharmacists who studied international research. The report is generated automatically.

Last update date: 2020-12-04 13:47:18

What is best to take for cystitis?

When analyzing what the difference is between Furadonin and Furagin, it is worth comparing their potential side effects. After all, a pharmacological drug for cystitis should not only be therapeutically effective, but also as safe as possible. Otherwise, after eliminating the cutting and burning sensation when urinating, you will have to treat the developed pathologies.

Furadonin has a slightly wider list of adverse reactions. They appear as follows:

• cough, chest pain, shortness of breath, bronchospasm;
• dyspeptic disorders;
• dizziness, headache, drowsiness;
• muscle pain;
• tremor;
• increased body temperature;
• dysbacteriosis;
• hepatitis;
• cholestatic syndrome;
• pancreatitis, pseudomembranous enterocolitis.

While taking Furagin can cause disorders of the gastrointestinal tract, dizziness, and reversible visual disturbances.

But still, Furadonin is usually the first choice drug in the treatment of cystitis. It has higher bioavailability, and a greater number of known pathogens are sensitive to its bacteriostatic effect.

The list of possible side effects is impressive, but they are observed much less frequently in clinical practice. Furadonin has a more advanced mechanism of pharmacological action, which affects the rate of recovery of patients.